The volume of research publications added every day to the human knowledge-base on PubMed central is overwhelming. Staying current with the most recent work in your field is critical for your success as a scientist. PubMed Alert Me! 1.0 is a free software tool that can help you to keep up-to-date with your favorite PubMed queries. PubMed Alert Me! 1.0 is a simple Windows platform software utility that allows you to enter a list of PubMed queries. Once you configure the program with your queries, a task is then scheduled to run either daily or weekly. The task searches PubMed using your queries and if it finds new matching published papers, the task sends an e-mail to you with a list of the new articles with links.